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When you're not into ITC Garamond:

The most distinctive element of [ITC Garamond] is its enormous lower-case x-height. In theory this improves its legibilty, but only in the same way that dog poop’s creamy consistency in theory should make it more edible.

(From: I Hate ITC Garamond - DesignObserver)

(via Eric Bailey)

Richard Rutter explains that maybe the ch unit isn't the best choice if you're trying to follow Robert Bringhurt's guidelines:

The important part of Bringhurst’s guideline is not the ’66-characters’ but the ‘satisfactory length’. This is about readability, and readability is affected by the length of a line more so than the number of characters in it.

(From: Use of ch unit considered inappropriate (in certain circumstances) | Clagnut by Richard Rutter)